Biochemical
Infometrics
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Consulting Services You can rely on
companies in search of external financing to tell you the upsides of
investing in their technology. They are usually not very good at
seeing the potential downsides, however. Our broad experience
in chemistry and biochemistry, taken together with our IP
experience, can provide a vital dose of caveat emptor complementary to that
provided by the investment candidate.
No matter how good
your development teams are, there will come a project or a point in
time where you just get stuck and need a fresh, external point of
view. Our backgrounds
combines
general chemistry, biochemistry, organic synthesis, physiology,
biometrics, statistics and
molecular modeling in a way that has a good chance of shedding new
light on information you already have
New descriptors and new
methods of
analysis are being developed all the time - in academia, at software
companies and in-house - and they often have a lot to offer. A
good validation is hard to do, though, and the job unfortunately often
falls to the least busy people in an organization rather than to the
most capable. Literature validation studies can be useful, but
they are often carried out in a context that doesn't quite fit with
what you want to do. Wouldn't it be a good idea to have an
independent party characterize a new method in terms of applicability,
reliability and accuracy before putting a lot of time and energy - not
to mention money - into it yourself?
Many
smaller biotech companies put off
bringing a molecular modeller until the need to do so is all too
obvious because they fear the sunk costs of hiring one. Unfortunately,
the need at that point is often painfully acute and the
situation so tangled up that it takes a very experienced - and
expensive -
person to untangle them. Getting part-time
modeling support early on can help you avoid this trap, pave the
way for hiring permanent in-house staff when the time comes, or find
out whether modelling can do anything for you. Our
direct synthesis experience is particularly valuable in such situations.
Customized training in
Computer-Aided Molecular Design (CAMD) is available from experts in the
field, with a particular emphasis on learning how to identify reliably
predictive structure - activity relationships (SARs). The
software available from Tripos and other vendors includes a lot of
powerful functionality, but some of it isn't as readily accessible as
one might wish for carrying out particular tasks, and most of it is
easy to mis-use. The combination of having devoted years to basic
research in the area and having created some of the most advanced
software available makes us uniquely qualified to train you in how to
get the most out of CAMD tools like GALAHAD to
effectively address
your particular problems.
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